spinosad insecticide dose drugs

Trifexis for Dogs: Uses, Dosage, Side Effects

Jun 29, 2020·The typically prescribed dose is a combination of 13.5mg/lb spinosad and 0.2mg/lb milbemycin oxime, given orally with food once a month [5]. Consult your vet regarding whether or not to crush the pills, as there is a lack of studies to show any difference in the effectiveness of the drug …

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Comfortis For Dogs | Veterinary Place

Comfortis is a once-monthly flea fighting formula based on the active ingredient spinosad, a natural substance derived from soil microbes. It is an insecticide which works by attacking a flea’s nervous system and comes in the form of chewable tablets, avoiding the discomfort of topical solutions and the risks associated with pets accidentally licking topically applied products.

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Laboratory evaluation of pyriproxyfen and spinosad, alone ...

Spinosad activity was -500 times lower than that of pyriproxyfen against the Bora strain, with LC50 and LC95 values estimated at 0.055 (0.047-0.064) and 0.20 (0.15-0.27) mg/liter, respectively. A binary mixture of pyriproxyfen and spinosad was realized at the ratio 1:500 by considering the values of the LC50 obtained for each product.

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Spinosad - ferti-lome

results, do not use more than 3 gallons of spray for 1000 sq ft of area. Do not use kitchen utensils for measuring. Keep measuring utensils with product and away from children. Unit of Measure† Amount of Natural Guard by ferti•lome® Spinosad to Use per Pint, Quart or Gallon of Spray Per Pint (16 fl. oz.) of Spray Per Quart (32 fl. oz.) of ...

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Pesticide Information about spinosad - UC IPM

Example home, garden or landscape use products 6. Bonide Captain Jack's Deadbug Brew Ready to Use • Captain Jack's Dead Bug Brew Ready to Spray • Captain Jack's Dead Bug Brew RTS • Captain Jack's Deadbug Brew Concentrate • Green Light Lawn & Garden Spray with Spinosad 2 • Monterey Garden Insect Spray • Orchard Rose & Flower Insect Spray Ready-to-Use • Trusted Since 1926 …

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Spinosad | Health Canada | Drug Product Database | DPD ...

Suppliers, 13 Gangwal Chemicals, 9 Sigachi Industries, 8 Roquette, 7 Microlex e.U, 5 BASF, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 4 Vasa Pharmachem, 3 DFE Pharma, 3 Kerry, 2 Finar, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 …

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SAFETY DATA SHEET - CDMS

In animals, Spinosad has been shown to cause vacuolization of cells in various tissues. Dose levels producing these effects were many times higher than any dose levels expected from exposure due to use. For the minor component(s): In animals, effects have been reported on the following organs after exposure to aerosols: Lung. Carcinogenicity

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What Is Comfortis (spinosad) Flea Treatment?

The introduction of spinosad for use in agriculture resulted in the receipt of a Presidential Green Chemistry Challenge Award 3 in 1999 from the U.S. Environmental Protection Agency. The award was presented to Dow AgroSciences LLC in the category of “Designing Safer Chemicals,” for the introduction of spinosad as an insect control product for use on crops.

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Pesticide Information about spinosad - UC IPM

Example home, garden or landscape use products 6. Bonide Captain Jack's Deadbug Brew Ready to Use • Captain Jack's Dead Bug Brew Ready to Spray • Captain Jack's Dead Bug Brew RTS • Captain Jack's Deadbug Brew Concentrate • Green Light Lawn & Garden Spray with Spinosad 2 • Monterey Garden Insect Spray • Orchard Rose & Flower Insect Spray Ready-to-Use • Trusted Since 1926 …

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Spinosad Insecticide: Subchronic and Chronic Toxicity and ...

Rats given 0.05% spinosad had similar numbers of neoplasms as control rats, indicating that spinosad was not carcinogenic at dose levels up to 0.05%. The NOEL at 2 years was 0.005% (2.4 mg/kg/day ...

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Spinosad General Fact Sheet

Spinosad Accession Number DB08823 Description. Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults. Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species.

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Spinosad Drug Information - Indications, Dosage, Side ...

Generic Name : Spinosad Pronunciation : SPIN-oh-sad Latest prescription information about Spinosad. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when ...

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Spinosad - Wikipedia

Spinosad is a novel mode-of-action insecticide derived from a family of natural products obtained by fermentation of S. spinosa.Spinosyns occur in over 20 natural forms, and over 200 synthetic forms (spinosoids) have been produced in the lab. Spinosad contains a mix of two spinosoids, spinosyn A, the major component, and spinosyn D (the minor component), in a roughly 17:3 ratio.

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Spinosad - an overview | ScienceDirect Topics

Spinosad can enhance the toxicity of ivermectin when used at a high dose (e.g., 0.6 mg/kg, against demodicosis) so it should not be administered in conjunction with ivermectin. Spinosad is a macrocyclic lactone and therefore should in theory be contraindicated for use on dogs with the MDR-1 mutation (see Chapter 5: Vulnerable

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Spinosad - an overview | ScienceDirect Topics

Spinosad can enhance the toxicity of ivermectin when used at a high dose (e.g., 0.6 mg/kg, against demodicosis) so it should not be administered in conjunction with ivermectin. Spinosad is a macrocyclic lactone and therefore should in theory be contraindicated for use on dogs with the MDR-1 mutation (see Chapter 5 : Vulnerable Patients).

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Spinosad | DrugBank Online

Spinosad Accession Number DB08823 Description. Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults. Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species.

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Spinosad Drug Information - Indications, Dosage, Side ...

Generic Name : Spinosad Pronunciation : SPIN-oh-sad Latest prescription information about Spinosad. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when ...

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SAFETY DATA SHEET - CDMS

In animals, Spinosad has been shown to cause vacuolization of cells in various tissues. Dose levels producing these effects were many times higher than any dose levels expected from exposure due to use. For the minor component(s): In animals, effects have been reported on the following organs after exposure to aerosols: Lung. Carcinogenicity

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One Up - Spinosad Insecticide, Best Caterpillar Killer Spray

One-up (Spinosad 45% SC) is a naturally derived insecticide of Macrocyclic lactone spinosyn group, which controls all stages of caterpillars by its contact and stomach action.Oneup causes excitation of the insect nervous system, leading to involuntary muscle contractions, prostration with …

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SPINOSAD « New Drug Approvals

Nov 01, 2020·Spinosad has recently been used in oral preparations (as Comfortis) to treat C. felis, the cat flea, in canines and felines; the optimal dose set for canines is reported to be 30 mg/kg. [2] Spinosad is sold under the trade names, Comfortis, Trifexis, and Natroba.

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Spinosad - Wikipedia

Spinosad is a novel mode-of-action insecticide derived from a family of natural products obtained by fermentation of S. spinosa.Spinosyns occur in over 20 natural forms, and over 200 synthetic forms (spinosoids) have been produced in the lab. Spinosad contains a mix of two spinosoids, spinosyn A, the major component, and spinosyn D (the minor component), in a roughly 17:3 ratio.

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Spinosad (Professional Patient Advice) - Drugs.com

Dec 14, 2020·Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 1 Mar 2021), …

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SPINOSAD « New Drug Approvals

Nov 01, 2020·Spinosad has recently been used in oral preparations (as Comfortis) to treat C. felis, the cat flea, in canines and felines; the optimal dose set for canines is reported to be 30 mg/kg. [2] Spinosad is sold under the trade names, Comfortis, Trifexis, and Natroba.

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Spinosad - an overview | ScienceDirect Topics

Spinosad can enhance the toxicity of ivermectin when used at a high dose (e.g., 0.6 mg/kg, against demodicosis) so it should not be administered in conjunction with ivermectin. Spinosad is a macrocyclic lactone and therefore should in theory be contraindicated for use on dogs with the MDR-1 mutation (see Chapter 5: Vulnerable

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Spinosad for Dogs - VetInfo

Spinosad is known more commonly by the name of the brand name label drug called Comfortis. Comfortis is a unique medicine in the group of drugs that are designed for use against fleas. The primary reason that this medicine stands out in comparison with the alternatives of its type is that it is the first medicine to be approved by the FDA which ...

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Insect nicotinic acetylcholine receptor agonists as flea ...

Therapeutic use of spinosad. Spinosad was introduced by Dow AgroSciences LLC for controlling the lepidopterous pests in cotton in 1997. In veterinary medicine, spinosad is an FDA‐approved oral drug for use as a flea adulticide. It is highly effective (97–100% 30 days after the treatment) and safe in dogs.

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